At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs, but few options.

Neurocrine Biosciences is a leading neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs, but few options. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, neuroendocrine, and neuropsychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, endometriosis* and uterine fibroids*, as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. For more information, visitneurocrine.com, and follow the company on LinkedIn, X (Formerly Twitter) and Facebook. (*in collaboration with AbbVie)

About the Role:

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• Designs, develops, and performs robust "fit-for-purpose" clinical biomarker assays

• Identifies and evaluates new technologies to support evolving translational biomarker strategies

• Capacity to perform lab work independently and direct the outsourcing of studies to CROs.

• Assists in the transition of biomarker assays from Basic Research to Clinical use by providing technical guidance on assay validation.

• Serves as a subject matter expert in immunoassay-based assay development and validation, collaborating with project teams, biomarker leaders, clinical operations and regulatory affairs on the implementation of these assays in clinical trials.

• Collaborates with external academic and industry experts to expand Neurocrine's knowledge base in biofluid biomarkers

• Generates and works with complex data sets, with a strong understanding of advanced dataanalysis and statistical tests

• Maintains and updates SOPs and writes data summaries for experiments conducted.

• Reviews, comprehends, and complies with all SOP's, and safety and quality assurance standards at all times.

• Provides training and/or supervision to junior staff, as needed.

• Other duties as assigned.

• BS/BA degree and 5+ years of relevant experience, OR

• MS/MA degree and 3+ years of relevant experience OR

• PhD or equivalent and some relevant experience; may include postdoc experience.

• Track record of successful implementation of immunoassays, proteomics, and cell-based assays (e.g., flow cytometry) for biomarker discovery using pre-clinical or clinical samples

• Extensive experience working with tissue samples and/or biofluids

• Experience with some of these techniques: ELISA, IP, western blotting, flow cytometry, high content imaging, HTRF

• Experience with managing contract research organizations

• Hands-on experience with the pros and cons of different biomarker assay platforms (eg. Luminex,

  MesoScale Discovery and/or SIMOA) is preferred.

• Exosome purification in humans and non-clinical species is a plus

• Experience working with human biospecimens is a plus

• Demonstrates solid level of understanding project / group goals and methods

• Consistently recognizes anomalous and inconsistent results and interprets experimental outcomes

• Able to explain the process behind the data and implications of the results

• Strong knowledge of one or more scientific disciplines, becoming expert in one discipline

• Strong knowledge of scientific principles, methods and techniques

• Strong knowledge and demonstrated ability working with a variety of laboratory equipment/tools

• Ability to work as part of a team; may train lower levels

• Excellent computer skills

• Strong communications, problem-solving, analytical thinking skills

• Detail-oriented yet can see broader picture of scientific impact on team

• Ability to meet multiple deadlines, with a high degree of accuracy and efficiency

• Strong project management skills

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Neurocrine Biosciences is an EEO/AA/Disability/Vets employer.

We are committed to building a diverse, equitable, and inclusive workplace, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don't line up to exactly what we have outlined in the job description.

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